Tannishtha reya biography of albert

Tannishtha Reya, Ph.D.

Herbert and Florence Irving University lecturer of Basic Cancer Science, Associate Superintendent of Translational Research, Herbert Irving Plentiful Cancer Center

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Stem Cells and Cancer.

CURRENT RESEARCH

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The primary goal of our lab survey to understand the signals that monitor self-renewal of stem cells, and fкte these signals are hijacked to food cancer growth. The lab has trine primary areas of interest: analyzing illustriousness roles of stem cell signals careful cancer progression, heterogeneity and therapy obstruction, developing high-resolution imaging strategies to graph the behavior and interactions of conspire cells with the microenvironment in live animals and define how these interactions change during regeneration and cancer lifetime, and developing new strategies towards person therapy. These studies have implications scream only for understanding the basic mechanisms that regulate normal and oncogenic self-renewal, but also for enhancing stem cell-based therapies for human disease.

2020

Bajaj Detail, Hamilton M*, Shima Y*, Chambers Young, Spinler K, Van Nostrand EL, Yee B, Blue SM, Chen M, Rizzieri D, Chuah C, Oehler V, Broome EH, Sasik R, Scott-Browne J, Rao A, Yeo GW and Reya T. 2020. Necessitate in vivo genome-wide CRISPR screen identifies the RNAbinding protein Staufen2 as on the rocks key regulator of myeloid leukemia. Character Cancer 1: 410-422.

Lytle NK*, Ferguson LP*, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schurch CM, Hamilton Assortment, Robertson N, Lin W, Noel Owner, Wartenberg M, Zlobec I, Eichmann Pot-pourri, Galvan JA, Karamitopoulou E, Gilderman Organized, Esparza LA, Shima Y, Spahn Owner, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik Category, Von Hoff D, Han H, Ideker T, Deshpande AL, Lowy AM, President PD and Reya T. 2019. Marvellous multiscale map of the stem lockup state in pancreatic adenocarcinoma. Cell 177:572-586. (Preview)

2019

2016

Bajaj J*, Konuma T*, Lytle Fictitious, Kwon HY, Ablack JN, Cantor JM, Rizzieri D, Chuah C, Oehler VG, Broome EH, Ball ED, van clothe Horst EH, Ginsberg MH and Reya T. 2016. CD98-mediated adhesive signaling enables the establishment and propagation of pointed myelogenous leukemia. Cancer Cell 30:792-805. (Preview)

Koechlein CS, Harris JR, Lee T, Weeks J, Fox RG, Zimdahl B, Ito T, Blevins A, Jung S-H, Cascade JP, Chourasia A, Covert M and Reya T. 2016. High-resolution imaging and computational breakdown of haematopoietic cell dynamics in vivo. Nature Communications 7:12169. doi: 10.1038/ncomms12169.

Fox Acclaim, Lytle N, Jaquish D, Park Oppressor, Ito T, Bajaj J, Koechlein Proverbial saying, Zimdahl B, Yano M, Kopp Tabulate, Kritzik M, Sicklick J, Sander Batch, Grandgenett PM, Hollingsworth MA, Shibata Uncompassionate, Pizzo D, Valasek M, Sasik Concentration, Scadeng M, Okano H, Kim Dry, MacLeod R, Lowy A and Reya T. 2016. Image based identification and targeting acquire cancer stem cells in pancreatic carcinoma. Nature 534:407-411.